Table 2.
Univariate logistic regression model to test association of AKI and initial serum chloride ([CL-]0), maximal serum chloride in first 48 hours ([Cl–]max), and increase in serum chloride (Δ[Cl-] = [Cl-]max–[CL-]0)
| Variable | AKI stage 1 to 3 | p | AKI stage 2 and 3 | p |
|---|---|---|---|---|
| Odds ratio (95 % CI) | Odds ratio (95 % CI) | |||
| [CL-]0 | 1.01 (0.97–1.05) | 0.478 | 0.99 (0.95–1.03) | 0.562 |
| [Cl-]max | 1.14 (1.08–1.20) | <0.001a | 1.07 (1.02–1.12) | 0.006a |
| Δ[CL-] | 1.25 (1.16–1.36) | <0.001a | 1.14 (1.07–1.21) | <0.001a |
AKI acute kidney injury, [Cl - ] 0 initial chloride concentration, [Cl - ] max maximal chloride concentration in the first 48 hours, Δ[Cl - ] increase in serum chloride, CI confidence interval
aIndicates statistical significance, p <0.05