Table 1.
Baseline characteristics of the participants
| Characteristic | Total |
|---|---|
| N (%) | |
| Age, years* | 62.3 ± 11.5 |
| Male gender | 1118 (68.5 %) |
| Smoking | 776 (47.6 %) |
| Diabetes mellitus | 508 (31.1 %) |
| Hypertension | 1372 (84.1 %) |
| Hypercholesterolemia | 723 (44.3 %) |
| Serum creatinine, umol/L | 77.4 (65.9–90.0) |
| eGFR, ml/min/1.73 m2 | 106.9 (89.3–127.9) |
| Atrial fibrillation | 69 (4.2 %) |
| Ischemic heart disease | 187 (11.5 %) |
| History of ischemic stroke/TIA | 434 (26.6 %) |
| CKD stages | |
| Stage 1 | 1211 (74.2 %) |
| Stage 2 | 362 (22.2 %) |
| Stage 3 | 54 (3.3 %) |
| Stage 4 | 5 (0.3 %) |
| Stage 5 | 0 (0 %) |
| PVH degrees | |
| Degree 0 | 293 (18.0 %) |
| Degree 1 | 749 (45.9 %) |
| Degree 2 | 416 (25.5 %) |
| Degree 3 | 174 (10.7 %) |
| SDWMH degrees | |
| Degree 0 | 811 (49.7 %) |
| Degree 1 | 575 (35.2 %) |
| Degree 2 | 131 (8.0 %) |
| Degree 3 | 115 (7.0 %) |
Variables are presented as mean ± SD (*), median (first-third quartile) or number (percentage)
Abbreviations: eGFR estimated glomerular filtration rate, CKD chronic kidney disease, PVH periventricular white matter hyperintensity, SDWMH subcortical deep white matter hyperintensity