Figure 2.

Cilia in mammalian kidney development. (A) Primary cilia are first seen on nonproliferating epithelial cells of the renal vesicle (RV) and ureteric bud (UB) during kidney development. (B) As the RV grows into a comma‐shaped early nephron, primary cilia remain on nonproliferating cells of the nascent nephron and growing UB as it expands the collecting duct system. (C) Nonproliferating cells of the collecting duct and S‐shaped nephron have primary cilia. (D) Primary cilia continue to be present on epithelial cells of the mature nephron tubule and collecting duct. Proliferating cells are drawn with a dividing nucleus.