Table 1.
Characteristics of included participants
| Group | N n (%) | Age mean (SD) | Male n (%) | CAG mean (SD) | Burden score mean (SD) | TFC mean (SD) | TMS mean (SD) |
|---|---|---|---|---|---|---|---|
| Total | 76 (100) | 47.9 (13.1) | 33 (43.4) | 43.8 (3.9)* | 389.1 (151.8)* | 8.6 (4.5)* | 34.6 (29.6)* |
| Healthy controls | 24 (31.6) | 45.1 (14.3) | 8 (33.3) | N/A | N/A | N/A | N/A |
| Pre‐manifest HD | 13 (17.1) | 39.5 (12.5) | 6 (46.2) | 42.4 (2.5) | 255.0 (100.5) | 12.6 (0.7) | 2.4 (2.7) |
| Early HD | 22 (29.0) | 49.3 (10.4) | 8 (36.3) | 44.1 (2.7) | 402.6 (84.9) | 10.8 (1.5) | 28.3 (15.7) |
| Moderate HD | 6 (7.9) | 59.6 (6.2) | 5 (83.3) | 41.7 (2.7) | 365.8 (149.3) | 5.0 (0.9) | 51.8 (21.1) |
| Advanced HD | 11 (14.5) | 54.5 (11.7) | 6 (54.5) | 46.1 (6.2) | 533.4 (179.2) | 1.4 (1.4) | 75.7 (15.8) |
HD, Huntington's disease; N/A, non‐applicable; SD, standard deviation; TFC, UHDRS total functional capacity; TMS, UHDRS total motor score *, excluding healthy controls.