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. 2016 Sep 23;19(3):308–315. doi: 10.4048/jbc.2016.19.3.308

Table 1. Ultrasonographic findings in benign and malignant breast lesions in patients with nipple discharge.

Variable Pathology
No. (%)
p-value
Benign
(n=59)
Malignant
(n=8)
Age (yr)* 46.8±11.3 52.5±16.6 0.456
Size (cm)* 1.1±4.2 1.4±8.7 0.377
Distance from the nipple (cm) 1.0 (0.0–6.0) 1.0 (0.0–7.0) 0.568
Tissue composition 0.497
 Homogeneous fat 2 (66.7) 1 (33.3)
 Homogeneous fibroglandular 28 (90.3) 3 (9.7)
 Heterogeneous 29 (87.9) 4 (12.1)
Shape 0.030
 Oval 40 (95.2) 2 (4.8)
 Round 9 (75.0) 3 (25.0)
 Irregular 10 (76.8) 3 (23.1)
Orientation 0.029
 Parallel 51 (97.7) 4 (7.3)
 Not parallel 8 (66.7) 4 (33.3)
Margin 0.278
 Circumscribed 21 (95.5) 1 (4.5)
 Indistinct 6 (75.0) 2 (25.0)
 Angular 1 (100.0) 0
 Microlobulated 29 (87.9) 4 (12.1)
 Spiculated 2 (66.7) 1 (33.3)
Echogenicity 0.609
 Hypoechoic 18 (90.0) 2 (10.0)
 Isoechoic 32 (84.2) 6 (15.8)
 Mixed (solid and cystic) 8 (100.0) 0
 Heterogeneous 1 (100.0) 0
Posterior features 0.444
 None 43 (87.8) 6 (12.2)
 Enhancement 14 (93.3) 1 (6.7)
 Shadowing 2 (66.7) 1 (33.3)
Calcification 1.000
 None 56 (87.5) 8 (12.5)
 Microcalcification in mass 3 (100.0) 0
Association with ducts 0.751
 Single mass not associated with duct 34 (85.0) 6 (15.0)
 Mass incompletely filling the duct 7 (100.0) 0
 Mass completely filling the duct or extending outside the duct 18 (90.0) 2 (10.0)
Adjacent ductal dilatation 0.465
 No 27 (84.4) 5 (15.6)
 Yes 32 (91.4) 3 (8.6)
Branch duct 0.554
 0 45 (88.2) 6 (11.8)
 1 12 (92.3) 1 (7.7)
 2 or more 2 (66.7) 1 (33.3)

*Mean±SD; Median (range); Seven among 34 benign lesions (20.6%) and one among six malignant lesions (16.7%) showed adjacent ductal changes.