Table 1. Ultrasonographic findings in benign and malignant breast lesions in patients with nipple discharge.
Variable | Pathology No. (%) |
p-value | |
---|---|---|---|
Benign (n=59) |
Malignant (n=8) |
||
Age (yr)* | 46.8±11.3 | 52.5±16.6 | 0.456 |
Size (cm)* | 1.1±4.2 | 1.4±8.7 | 0.377 |
Distance from the nipple (cm)† | 1.0 (0.0–6.0) | 1.0 (0.0–7.0) | 0.568 |
Tissue composition | 0.497 | ||
Homogeneous fat | 2 (66.7) | 1 (33.3) | |
Homogeneous fibroglandular | 28 (90.3) | 3 (9.7) | |
Heterogeneous | 29 (87.9) | 4 (12.1) | |
Shape | 0.030 | ||
Oval | 40 (95.2) | 2 (4.8) | |
Round | 9 (75.0) | 3 (25.0) | |
Irregular | 10 (76.8) | 3 (23.1) | |
Orientation | 0.029 | ||
Parallel | 51 (97.7) | 4 (7.3) | |
Not parallel | 8 (66.7) | 4 (33.3) | |
Margin | 0.278 | ||
Circumscribed | 21 (95.5) | 1 (4.5) | |
Indistinct | 6 (75.0) | 2 (25.0) | |
Angular | 1 (100.0) | 0 | |
Microlobulated | 29 (87.9) | 4 (12.1) | |
Spiculated | 2 (66.7) | 1 (33.3) | |
Echogenicity | 0.609 | ||
Hypoechoic | 18 (90.0) | 2 (10.0) | |
Isoechoic | 32 (84.2) | 6 (15.8) | |
Mixed (solid and cystic) | 8 (100.0) | 0 | |
Heterogeneous | 1 (100.0) | 0 | |
Posterior features | 0.444 | ||
None | 43 (87.8) | 6 (12.2) | |
Enhancement | 14 (93.3) | 1 (6.7) | |
Shadowing | 2 (66.7) | 1 (33.3) | |
Calcification | 1.000 | ||
None | 56 (87.5) | 8 (12.5) | |
Microcalcification in mass | 3 (100.0) | 0 | |
Association with ducts | 0.751 | ||
Single mass not associated with duct | 34 (85.0)‡ | 6 (15.0)‡ | |
Mass incompletely filling the duct | 7 (100.0) | 0 | |
Mass completely filling the duct or extending outside the duct | 18 (90.0) | 2 (10.0) | |
Adjacent ductal dilatation | 0.465 | ||
No | 27 (84.4) | 5 (15.6) | |
Yes | 32 (91.4) | 3 (8.6) | |
Branch duct | 0.554 | ||
0 | 45 (88.2) | 6 (11.8) | |
1 | 12 (92.3) | 1 (7.7) | |
2 or more | 2 (66.7) | 1 (33.3) |
*Mean±SD; †Median (range); ‡Seven among 34 benign lesions (20.6%) and one among six malignant lesions (16.7%) showed adjacent ductal changes.