Table 3.
IPD NMA ANCOVA synthesis model results (model 1), EQ-5D preference score and standardised pain endpoints
| IPD NMA ANCOVA results: EQ-5D preference score and SMD endpointsa | Model 1, ANCOVA, change in outcome score, adjusted for baseline median MCMC posterior sample (95 % CrI) | |||
|---|---|---|---|---|
| Change EQ-5D | Change standardised pain | |||
| Relative treatment effects | Osteoarthritis of the knee | SHAM vs UC | 0.057 (0.013, 0.095) | 0.271 (-0.007, 0.537) |
| ACU vs UC | 0.079 (0.042, 0.114) | 0.703 (0.399, 0.984) | ||
| ACU vs SHAM | 0.022 (-0.014, 0.060) | 0.438 (0.121, 0.715) | ||
| Headache | SHAM vs UC | 0.052 (0.010, 0.095) | 0.332 (0.022, 0.669) | |
| ACU vs UC | 0.056 (0.021, 0.092) | 0.588 (0.311, 0.869) | ||
| ACU vs SHAM | 0.004 (-0.035, 0.042) | 0.256 (-0.073, 0.560) | ||
| Musculoskeletal | SHAM vs UC | 0.059 (0.017, 0.101) | 0.063 (-0.241, 0.378) | |
| ACU vs UC | 0.082 (0.047, 0.116) | 0.588 (0.334, 0.863) | ||
| ACU vs SHAM | 0.023 (-0.008, 0.053) | 0.527 (0.323, 0.735) | ||
| Between-study variance | 0.001 (0, 0.003) | 0.090 (0.049, 0.170) | ||
| Total residual deviance b | 15,850 (15,480; 16, 230) | 17,060 (16,660; 17,450) | ||
| Deviance information criterion c | -6,420.4 | 37,394.2 | ||
a UC usual care, SHAM sham acupuncture, ACU acupuncture, Headache group headache, migraine and TTH, Musculoskeletal group neck, shoulder and low back pain
bFor the EQ-5D endpoint models used approx. 14800 observations; for the SMD endpoint models used approx. 15900. Models should be preferred when total residual deviance mean posterior is close to the actual number of data points
cDeviance information criterion (DIC) is a statistical measure of model fit and model comparison. Models with smaller DIC are preferred