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The correlation between the druggability of examined PTPs and their pocket size, enclosure and hydrophilicity.
Notes: (A) The correlation between Dscore values obtained by the 17 PTPs and their pocket size and enclosure. (B) The correlation between PTPs’ Dscore values and the hydrophilicity of their pockets.
Abbreviations: Dscore, druggability score; PTP, protein tyrosine phosphatase.
