Fig 1. Major metabolic pathways leading to fumarate formation in T. glabrata.
Boldface arrows indicate variants for fumarate synthesis implemented in strains featured in this study. RoPYC: pyruvate carboxylase from R. oryzae; RoMDH: malate dehydrogenase from R. oryzae; RoFUM: fumarase from R. oryzae; SpMAE1: C4-dicarboxylic acid transporter from Schizosaccharomyces pombe; ade12: adenylosuccinate synthase; ade13: adenylosuccinate lyase; amd1: AMP deaminase.
