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. 2016 Jun 13;15(19):2593–2607. doi: 10.1080/15384101.2016.1198862

Figure 1.

Figure 1.

Flowchart depicting the strategy to identify core GECN in HeLa and ES cells. In this study, we mined omics information from big databases, such as transcription and miRNA regulation interactions, to construct real GECNs using genome-wide high-throughput data, a dynamic model, and AIC. For drug screening, information was integrated from cervical carcinogenic mechanisms in cancer-specific GECN and drug databases for cervical cancer treatment.