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. 2016 Jun 13;15(19):2593–2607. doi: 10.1080/15384101.2016.1198862

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© 2016 The Author(s). Published with license by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 6. — Carcinogenic and stemness mechanisms. (A) Carcinogenic mechanism of HeLa cells and (B) stemness mechanism of ES cells. Carcinogenic and stemness mechanisms were derived by applying big mechanism analysis to the principal GECN in HeLa and ES cells, respectively (Fig. 5 A and B), using the gene ontology tool DAVID. Genes/TFs/miRNAs in blue and red denote activated expression in HeLa and ES cells, respectively (p-value ≤ 0.05).