Table 2. The BH₄% in the blood, liver and kidney after 6RBH₄ administration.

Time	Rat group	Blood	Liver 1)		Kidney 1), 2)
		%	%		%
30 min	BH4 alone	93.9 ±0.6	98.7 ±0.1	**	98.0 ±0.2	**, n.s.
	BH4 + Pbc	89.2 ±0.7	98.7±0.1	**	97.7 ±0.3	**, n.s.
	BH4 + CsA	94.4 ±0.1	98.6 ±0.1	**	98.1 ±0.4	**, n.s.
120 min	BH4 alone	96.2 ±0.1	98.8 ±0.1	**	98.6 ±0.3	**, n.s.
	BH4 + Pbc	87.6 ±3.7	98.1 ±0.1	n.s.	89.2 ±5.5	n.s., n.s.
	BH4 + CsA	95.3 ±0.1	98.5 ±0.1	**	98.4 ±0.1	**, n.s.

The BH₄% in organs 30 min and 120 min after administration of 6RBH₄ with or without prior treatment with Pbc or CsA. For each rat group, differences in the organ BH₄% between blood, liver and kidney were analyzed by Tukey’s multiple testing method. BH₄% values are means ±S.E. and apply to Fig 5.

¹⁾ Difference between the BH₄% of time-matched blood vs. liver or kidney. **P<0.01 significance, suggesting the BH₄% is higher than that of blood; “n.s.”, not significant.

²⁾ Difference between the BH₄% of time-matched liver vs. kidney.