Table 4. Covariantly upregulated genes in cGMP-hBM-MSC treated with OM-FBS or OM-PL for two weeks (2W) or one week (1W).
| Differentiation | Covariant Genes | Correlation | p-value |
|---|---|---|---|
| Protocol | (r2) | ||
| 2W-OM-FBS | ALPL-BGN | 0.987 | 2.50E-04 |
| BGLAP-DLX5 | 0.850 | 0.032 | |
| CLEC3B-COL1A1 | 1.000 | 1.60E-07 | |
| CLEC3B-COLIA2 | 0.994 | 4.90E-05 | |
| COL1A1-COL1A2 | 0.995 | 3.80E-05 | |
| 2W-OM-PL | BGLAP-MKI67 | 0.960 | 0.002 |
| BGN-CADM1 | 0.946 | 0.004 | |
| BGN-COL1A1 | 0.995 | 3.40E-05 | |
| BGN-ELN | 0.832 | 0.040 | |
| BGN-RUNX2 | 0.998 | 3.90E-06 | |
| CADM1-COL1A1 | 0.927 | 0.008 | |
| CADM1-RUNX2 | 0.932 | 0.007 | |
| CLEC3B-COL1A2 | 0.878 | 0.021 | |
| COL1A1-ELN | 0.822 | 0.045 | |
| COL1A1-RUNX2 | 0.996 | 2.60E-05 | |
| ELN-RUNX2 | 0.846 | 0.034 | |
| 1W-OM-FBS | ALPL-BGN | 0.995 | 3.00E-05 |
| ALPL-COL1A1 | 0.840 | 0.037 | |
| ALPL-ELN | 0.995 | 4.00E-05 | |
| BGN-COL1A1 | 0.868 | 0.025 | |
| BGN-ELN | 0.999 | 3.20E-06 | |
| COL1A1-ELN | 0.859 | 0.029 | |
| DCN-MKI67 | 0.898 | 0.015 | |
| 1W-OM-PL | ALPL-CLEC3B | 0.881 | 0.020 |
| BGN-COL1A1 | 0.856 | 0.029 | |
| BGN-ELN | 0.902 | 0.014 | |
| BGN-RUNX2 | 0.993 | 6.60E-05 | |
| CADM1-COL1A1 | 0.869 | 0.025 | |
| COL1A1-RUNX2 | 0.820 | 0.046 | |
| ELN-RUNX2 | 0.936 | 0.006 |
(r2): coefficient of determination.