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. 2016 Mar 24;7(19):27094–27107. doi: 10.18632/oncotarget.8314

Figure 2. CrkI and CrkII overexpression induces EMT via distinct regulation of Rac1 and RhoA.

Figure 2

A. qRT-PCR analysis of mRNA expression of Snail and Slug. Effects of ROCK inhibitor Y27632 (10 μM) and Rac1 inhibitor NSC23766 (50 μM) were also analyzed. B. qRT-PCR analysis of mRNA expression of E-cadherin, N-cadherin, fibronectin, and MMP2. Values are means±SD from three independent experiments. *P < 0.05 versus control cells. P < 0.05 versus untreated cells.