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. 2016 Mar 25;7(19):27142–27157. doi: 10.18632/oncotarget.8382

Figure 5. The p53 pathway mediates cell proliferation and metabolic defects induced by PFKP suppression in kidney cancer cells.

Figure 5

A. Western blot analysis for Caki-1 cells stably transfected with shRNAs for control (shCtrl) or p53 (shp53). B.-I. Caki-1 cells stably transfected with shCtrl or shp53 were transiently transfected with siCtrl or siPFKP1 and subjected to various analysis including Western blot (B), real time PCR (C), Brdu incorporation (D), annexin V and PI staining (F), glucose uptake (G), lactate production (H) and oxygen consumption rate (I) at 72 hours after transfection. * indicates p < 0.05 in C, E-I.