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. 2016 Mar 27;7(19):27295–27306. doi: 10.18632/oncotarget.8422

Figure 6. Mcl-1 is essential for MM cell survival.

Figure 6

(A) Expression of Mcl-1 protein in human myeloma cell lines INA-6-MOCK and INA-6-PRL-3 transfected with control- or Mcl-1-siRNA. (B) After transfection with siRNA, cells were grown for 48 hours in 10% FBS in RPMI with 1 ng/mL IL-6 before viability was determined by annexin V-Alexa647 flow cytometry. Percentage of viable Mcl-1 knockdown cells was calculated as relative to viable cells in control. Figure shows one representative experiment of three.