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. 2016 Mar 30;7(19):27538–27551. doi: 10.18632/oncotarget.8485

Table 2. Relationship between GSK-3β expression and clinicopathological features of endometrial carcinomas.

Variables GSK-3β (− = 0, + = 1, ++ = 2, +++ = 3) Total PR (%) X2 P value
0 1 2 3
The pathology types 3.019 0.385
Endometrioid adenocarcinoma 86 46 7 2 141 39.01
The other pathology types 11 2 0 0 13 15.38
Age 1.131 0.790
< 55 46 24 2 1 73 36.99
≥ 55 51 24 5 1 81 37.04
BMI (WHO) 2.955 0.450
< 25 57 21 4 1 83 31.33
≥ 25 40 27 3 1 71 43.66
Diabetes 3.762 0.297
No 69 28 6 1 104 33.65
Yes 28 20 1 1 50 44.00
Hypertension 1.534 0.700
No 70 34 4 2 110 36.36
Yes 27 14 3 0 44 38.64
FIGO stages 14.592 0.006
I + II 90 34 5 1 130 30.77
III + IV 7 14 2 1 24 70.83
Pathology classification 22.641 0.006
Well + Mod 89 45 7 0 141 36.88
Poor 8 3 0 2 13 38.46
The depth of myometrial infiltration 8.698 0.026
< 1/2 74 30 6 0 110 32.73
≥ 1/2 23 18 1 2 44 47.73
Lymph node metastasis 7.226 0.065
Negative 92 45 6 1 144 36.11
Positive 5 3 1 1 10 50.00
ER 3.603 0.299
28 12 0 0 40 30.00
+ 69 36 7 2 114 39.47
PR 3.546 0.289
23 14 0 0 37 37.84
+ 74 34 7 2 117 36.75
Positive ascites cytology 4.879 0.182
Negative 68 35 5 0 108 37.04
Positive 29 13 2 2 46 36.96

Abbreviations: PR = positive rate; Bold represents for P < 0.05.