Table 2. Relationship between GSK-3β expression and clinicopathological features of endometrial carcinomas.
| Variables | GSK-3β (− = 0, + = 1, ++ = 2, +++ = 3) | Total | PR (%) | X2 | P value | |||
|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | |||||
| The pathology types | 3.019 | 0.385 | ||||||
| Endometrioid adenocarcinoma | 86 | 46 | 7 | 2 | 141 | 39.01 | ||
| The other pathology types | 11 | 2 | 0 | 0 | 13 | 15.38 | ||
| Age | 1.131 | 0.790 | ||||||
| < 55 | 46 | 24 | 2 | 1 | 73 | 36.99 | ||
| ≥ 55 | 51 | 24 | 5 | 1 | 81 | 37.04 | ||
| BMI (WHO) | 2.955 | 0.450 | ||||||
| < 25 | 57 | 21 | 4 | 1 | 83 | 31.33 | ||
| ≥ 25 | 40 | 27 | 3 | 1 | 71 | 43.66 | ||
| Diabetes | 3.762 | 0.297 | ||||||
| No | 69 | 28 | 6 | 1 | 104 | 33.65 | ||
| Yes | 28 | 20 | 1 | 1 | 50 | 44.00 | ||
| Hypertension | 1.534 | 0.700 | ||||||
| No | 70 | 34 | 4 | 2 | 110 | 36.36 | ||
| Yes | 27 | 14 | 3 | 0 | 44 | 38.64 | ||
| FIGO stages | 14.592 | 0.006 | ||||||
| I + II | 90 | 34 | 5 | 1 | 130 | 30.77 | ||
| III + IV | 7 | 14 | 2 | 1 | 24 | 70.83 | ||
| Pathology classification | 22.641 | 0.006 | ||||||
| Well + Mod | 89 | 45 | 7 | 0 | 141 | 36.88 | ||
| Poor | 8 | 3 | 0 | 2 | 13 | 38.46 | ||
| The depth of myometrial infiltration | 8.698 | 0.026 | ||||||
| < 1/2 | 74 | 30 | 6 | 0 | 110 | 32.73 | ||
| ≥ 1/2 | 23 | 18 | 1 | 2 | 44 | 47.73 | ||
| Lymph node metastasis | 7.226 | 0.065 | ||||||
| Negative | 92 | 45 | 6 | 1 | 144 | 36.11 | ||
| Positive | 5 | 3 | 1 | 1 | 10 | 50.00 | ||
| ER | 3.603 | 0.299 | ||||||
| − | 28 | 12 | 0 | 0 | 40 | 30.00 | ||
| + | 69 | 36 | 7 | 2 | 114 | 39.47 | ||
| PR | 3.546 | 0.289 | ||||||
| − | 23 | 14 | 0 | 0 | 37 | 37.84 | ||
| + | 74 | 34 | 7 | 2 | 117 | 36.75 | ||
| Positive ascites cytology | 4.879 | 0.182 | ||||||
| Negative | 68 | 35 | 5 | 0 | 108 | 37.04 | ||
| Positive | 29 | 13 | 2 | 2 | 46 | 36.96 | ||
Abbreviations: PR = positive rate; Bold represents for P < 0.05.