Skip to main content
. 2016 Mar 30;7(19):27665–27675. doi: 10.18632/oncotarget.8491

Table 2. Association between PSCA SNPs and age of breast cancer patients.

Age(years) genotype distributions(case/control) Co-dominant Dominant Recessive Allele
AA Aa aa P OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI)
rs2294008
<49 135/157 128/131 31/23 0.46m
0.13n
1.14(0.81-1.59)m
1.57(0.87-2.82)n
0.26 1.20 (0.87-1.65) 0.18 1.48 (0.84-2.60) 0.15 1.20 (0.94-1.53)
≥49 138/142 103/116 25/14 0.62m
0.08n
0.91(0.64-1.30)m
1.84(0.92-3.68)n
0.94 1.01 (0.72-1.42) 0.06 1.91 (0.97-3.76) 0.40 1.12 (0.86-1.47)
rs2976392
<49 156/163 117/130 21/18 0.72m
0.56n
0.94(0.67-1.31)m
1.22(0.63-2.37)n
0.87 0.97 (0.71-1.34) 0.50 1.25 (0.65-2.40) 0.89 1.02 (0.79-1.31)
≥49 131/135 113/117 22/20 0.98m
0.71n
1.00(0.70-1.42)m
1.13(0.59-2.18)n
0.93 1.02 (0.72-1.42) 0.90 0.98 (0.70-1.38) 0.81 1.03 (0.79-1.34)
rs2978974
<49 135/159 142/138 17/14 0.25m
0.34n
1.21(0.87-1.68)m
1.43(0.68-3.01)n
0.20 1.23 (0.90-1.70) 0.48 1.30 (0.63-2.69) 0.21 1.17 (0.91-1.51)
≥49 119/124 117/118 29/30 0.86m
0.98n
1.03(0.72-1.48)m
1.01(0.57-1.78)n
0.87 1.03 (0.73-1.44) 0.98 1.00 (0.58-1.70) 0.92 1.01 (0.79-1.31)

A: Major allele; a: Minor allele;

m= Heterozygote model;

n= Homozygote model; OR: odds ratio; 95%CI: confidence interval.