Table 3. Comparison of tumor responses according to the RECIST version 1.1 and PERCIST criteria.
| Tumor response by RECIST 1.1 | Tumor response by PERCIST | Total | |||
|---|---|---|---|---|---|
| CMR | PMR | SMD | PMD | ||
| CR | 3 | 0 | 0 | 0 | 3 |
| PR | 16 | 30 | 1 | 0 | 47 |
| SD | 4 | 18 | 23 | 6 | 51 |
| PD | 1 | 0 | 0 | 47 | 48 |
| Total | 24 | 48 | 24 | 53 | 149 |
Abbreviations: CMR, complete metabolic response; CR, complete response; PMD, progressive metabolic disease; PD, progressive disease; PERCIST, PET Response Criteria in Solid Tumors; PMR, partial metabolic response; PR, partial response; RECIST, Response Evaluation Criteria in Solid Tumors; SD, stable disease; SMD, stable metabolic disease.
The level of concordance of tumor responses between the RECISI 1.1 and PERCIST is 0.689 (liner weighted k, with 95% confidence interval, 0.612-0.763).
The overall response rates were significantly different between two criteria (33.6% by the RECIST vs. 48.3% by the PERCIST, P = 0.010)