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. 2016 Mar 30;7(19):28013–28026. doi: 10.18632/oncotarget.8472

Figure 3. HBx is able to activate the core region −1199/−803nt in promoter of C4BPα.

Figure 3

A. The relative activities of different regions of C4BPα promoter were examined by luciferase reporter gene assays in HepG2 (or H7402) cells. B. The relative activities of the core promoter (−1500/−803nt) of C4BPα were detected by luciferase reporter gene assays in HepG2 cells or H7402 cells transiently transfected with pCDNA3.1-HBx. C. The relative activities of the core promoter (−1500/−803nt) of C4BPα were detected by luciferase reporter gene assays in HepG2-X cells (or H7402-X) transiently transfected with HBx siRNA. D. The relative activities of the core promoter (−1199/−803nt) of C4BPα were detected by luciferase reporter gene assays in HepG2 cells or H7402 cells transiently transfected with pCDNA3.1-HBx. E. The relative activities of the core promoter (−1199/−803nt) of C4BPα were detected by luciferase reporter gene assays in HepG2-X cells (or H7402-X) transiently transfected with HBx siRNA. *p<0.05, **p<0.01, Student's t-test. All experiments were performed at least three times.