. 2016 Mar 30;7(19):28112–28123. doi: 10.18632/oncotarget.8492

Table 5. Stratification analysis for associations between selected and combined genotypes and gastric cancer risk in an eastern Chinese population.

Variables	STAT3 rs1053004 (cases/controls)		Crude OR (95% CI)	P^a	Adjusted OR (95% CI)	P^a	NRG^* (cases/controls)		Crude OR (95% CI)	P^a	Adjusted OR (95% CI)	P^a
Variables	AA	AG+GG	Crude OR (95% CI)	P^a	Adjusted OR (95% CI)	P^a	0 genotypes	1-2 genotypes	Crude OR (95% CI)	P^a	Adjusted OR (95% CI)	P^a
Age
≤ 59	216/194	362/421	0.77 (0.61-0.98)	0.035	0.67 (0.46-1.00)	0.048	206/252	411/408	1.20 (0.95-1.52)	0.132	1.21 (0.95-1.53)	0.122
> 59	229/238	318/368	0.90 (0.71-1.14)	0.371	0.95 (0.75-1.12)	0.687	159/222	349/339	1.45 (1.15-1.86)	0.002	1.43 (1.12-1.84)	0.005
Sex
Females	150/137	175/239	0.67 (0.49-0.91)	0.009	0.68 (0.50-0.92)	0.014	119/146	206/230	1.10 (0.81-1.49)	0.547	1.10 (0.81-1.49)	0.557
Males	295/295	505/550	0.92 (0.75-1.12)	0.407	0.94 (0.76-1.15)	0.534	246/328	554/517	1.43 (1.17-1.75)	0.001	1.45 (1.18-1.78)	0.0004
Smoking status
Never	295/222	395/400	0.74 (0.60-0.93)	0.001	0.73 (0.59-0.92)	0.007	232/254	458/364	1.36 (1.09-1.71)	0.007	1.33 (1.06-1.67)	0.013
Ever	150/210	285/389	1.02 (0.79-1.33)	0.848	1.02 (0.80-1.33)	0.859	133/220	302/379	1.32 (1.01-1.72)	0.040	1.30 (1.00-1.70)	0.049
Drinking status
Never	352/324	507/549	0.85 (0.70-1.03)	0.100	0.84 (0.69-1.03)	0.088	284/333	575/540	1.25 (1.03-1.52)	0.027	1.25 (1.03-1.53)	0.029
Ever	93/108	173/240	0.84 (0.60-1.18)	0.304	0.86 (0.61-1.20)	0.366	81/220	302/379	1.56 (1.10-2.18)	0.010	1.55 (1.10-2.18)	0.011

NRG: number of risk genotypes of IL6 rs2069837AG/GG and JAK1 rs2230587GA/GG.

Obtained in logistic regression models without (crude) and with adjustment for age, sex, smoking and drinking status.