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. 2016 Apr 5;7(19):28207–28217. doi: 10.18632/oncotarget.8593

Table 1. Correlation between Sp1, COX2 and clinicopathological features of PDAC patients.

Factors N Sp1 COX2
Negative Positive P-value Negative Positive P-value
Gender
Male 56 21 35 0.56 17 39 0.83
Female 32 14 18 9 23
Age
≤60 41 17 24 0.76 11 30 0.60
>60 47 18 29 15 32
T stage
≤T2 74 31 43 0.35 20 54 0.38
T3 14 4 10 6 8
N stage
N0 52 26 26 0.02* 20 32 0.03*
N1 36 9 27 6 30
Primary tumor location
Body and Tail 30 15 15 0.16 8 22 0.67
Head and Neck 58 20 38 18 40
Lymphovascular invasion
No 50 22 28 0.35 15 35 0.92
Yes 38 13 25 11 27
Nuclear grade
≤II 73 31 42 0.26 19 54 0.20
>II 15 4 11 7 8
Jaundice
No 62 28 34 0.11 20 42 0.39
Yes 26 7 19 6 20
Abdominal pain
No 39 14 25 0.51 15 24 0.10
Yes 49 21 28 11 38

Abbreviation: N, number; Sp1, specificity protein 1; COX2, cyclooxygenase-2. *P < 0.05 indicates a significant association among the variables.