Table 1. Correlation between Sp1, COX2 and clinicopathological features of PDAC patients.
| Factors | N | Sp1 | COX2 | ||||
|---|---|---|---|---|---|---|---|
| Negative | Positive | P-value | Negative | Positive | P-value | ||
| Gender | |||||||
| Male | 56 | 21 | 35 | 0.56 | 17 | 39 | 0.83 |
| Female | 32 | 14 | 18 | 9 | 23 | ||
| Age | |||||||
| ≤60 | 41 | 17 | 24 | 0.76 | 11 | 30 | 0.60 |
| >60 | 47 | 18 | 29 | 15 | 32 | ||
| T stage | |||||||
| ≤T2 | 74 | 31 | 43 | 0.35 | 20 | 54 | 0.38 |
| T3 | 14 | 4 | 10 | 6 | 8 | ||
| N stage | |||||||
| N0 | 52 | 26 | 26 | 0.02* | 20 | 32 | 0.03* |
| N1 | 36 | 9 | 27 | 6 | 30 | ||
| Primary tumor location | |||||||
| Body and Tail | 30 | 15 | 15 | 0.16 | 8 | 22 | 0.67 |
| Head and Neck | 58 | 20 | 38 | 18 | 40 | ||
| Lymphovascular invasion | |||||||
| No | 50 | 22 | 28 | 0.35 | 15 | 35 | 0.92 |
| Yes | 38 | 13 | 25 | 11 | 27 | ||
| Nuclear grade | |||||||
| ≤II | 73 | 31 | 42 | 0.26 | 19 | 54 | 0.20 |
| >II | 15 | 4 | 11 | 7 | 8 | ||
| Jaundice | |||||||
| No | 62 | 28 | 34 | 0.11 | 20 | 42 | 0.39 |
| Yes | 26 | 7 | 19 | 6 | 20 | ||
| Abdominal pain | |||||||
| No | 39 | 14 | 25 | 0.51 | 15 | 24 | 0.10 |
| Yes | 49 | 21 | 28 | 11 | 38 | ||
Abbreviation: N, number; Sp1, specificity protein 1; COX2, cyclooxygenase-2. *P < 0.05 indicates a significant association among the variables.