Table 1. Analysis of the histological tumor sections of the vehicle-treated and the genistein-treated A431 tumor mice (VEC-A431 and GEN-A431, respectively) and of the vehicle-treated and the genistein-treated Colo205 tumor mice (VEC-Colo205 and GEN-Colo205, respectively).
| VEC-A431 | GEN-A431 | VEC-Colo205 | GEN-Colo205 | |
|---|---|---|---|---|
| Mean [%] ± SD | Mean [%] ± SD | Mean [%] ± SD | Mean [%] ± SD | |
| H & E | 36.2 ± 9.4 | 19.4 ± 5.6 | 20.4 ± 12.3 | 13.7 ± 5.2 |
| GLUT1 | 99.7 ± 0.7 | 98.6 ± 3.0 | 74.9 ± 7.6 | 94.2 ± 2.9 |
| GLUT3 | 13.0 ± 9.2 | 67.5 ± 19.1 | 60.4 ± 20.5 | 78.0 ± 12.1 |
| GLUT4 | neg. | neg. | neg. | neg. |
| KI67 | 72.5 ± 7.9 | 84.2 ± 9.0 | 39.7 ± 13.3 | 76.9 ± 7.9 |
| TK-1 | 50.0 ± 8.2 | 72.8 ± 7.8 | 16.8 ± 4.0 | 34.9 ± 4.4 |
| Cleaved Caspase 3 | 11.0 ± 2.6 | 8.8 ± 2.0 | 8.4 ± 1.8 | 18.8 ± 2.8 |
The H & E results show the mean % necrosis of the tumor tissue, the immunohistochemistry results show the mean % positive cells within viable tumor regions.