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. 2016 Apr 5;7(19):28262–28272. doi: 10.18632/oncotarget.8596

Figure 7. Immunohistochemical analysis of xenograft tumors for expression of Ki-67 and pEGFR in late therapeutic strategy.

Figure 7

Tumors stained and quantified as in Fig. 6. Treated animals exhibited reduced Ki-67 and pEGFR staining compared with control cohorts (p < 0.001, except for Ki-67 in DiFi xenograft tumors p < 0.01). A. Representative images collected from control (n=6) and treated (n=10) mice. Scale bars, 100μm. B. The graphs of percentage area positive for Ki-67 and pEGFR in tumor specimens. Values are expressed as mean ± SEM. Statistical significance was assessed by one-way ANOVA with Tukey adjustment: *p < 0.05; **p < 0.01; ***p < 0.001; ns (not significant).