Skip to main content
. 2016 Apr 7;7(19):28435–28447. doi: 10.18632/oncotarget.8633

Figure 1. TSC2 positively regulates COX2 expression.

Figure 1

A. Tsc2+/+ and Tsc2−/− MEFs. B. pLXIN (V), pLXIN-hTSC2, or pLXIN-mut-hTSC2 retroviruses infected Tsc2−/− MEFs. C. ELT3 cells were transduced using retroviruses harboring hTSC2 in pLXIN or its control vector pLXIN (V). A-C. Cell lysates were subjected to immunoblotting with the indicated antibodies (left panel). COX2 mRNA was analyzed by qRT-PCR (right panel). Error bars indicate mean ± SD of triplicate samples. **P<0.01; ***P<0.001. D. Kidney cystadenomas (Tumor) and the adjacent normal tissues (Normal) from Tsc2+/− mice were immunoblotted with the indicated antibodies.