Table 1. Clinicopathological characteristics of AFP producing and non-producing gastric cancer.
| AFP producing GC | AFP non-producing GC | p Value | |
|---|---|---|---|
| No. of patients | 32 (41.6%) | 45 (58.4%) | N/A |
| Serum AFP (ng/ml) | 117.3±254.5 | 2.5±1.0 | 0.030* |
| Mean age (years) | 60.2±11.1 | 63.1±11.3 | 0.262 |
| Gender (M/F) | 26/6 | 33/12 | 0.299 |
| Drink (Y/N) | 9/23 | 11/34 | 0.456 |
| Smoke (Y/N) | 15/17 | 14/31 | 0.121 |
| Tumor size (cm) | 6.2±2.5 | 5.7±2.1 | 0.379 |
| Vascular invasion (Y/N) | 28/4 | 39/6 | 0.598 |
| Tumor site | |||
| Proximal (cardia or fundus) | 12 | 17 | 0.586 |
| Distal (antrum or corpus) | 20 | 28 | |
| Histology (poor/well or moderate) | 23/9 | 34/11 | 0.458 |
| Curative surgery (Y/N) | 27/5 | 43/2 | 0.110 |
| TNM stage | |||
| Ib | 1 | 1 | 0.226 |
| IIb | 4 | 6 | |
| IIIa | 2 | 0 | |
| IIIb | 5 | 13 | |
| IIIc | 15 | 23 | |
| IV | 5 | 2 | |
| Lymphatic invasion (Y/N) | 24/8 | 40/5 | 0.100 |
| Outcome | |||
| Relapse (Y/N) | 27/5 | 28/17 | 0.029* |
| Liver metastasis (Y/N) | 20/12 | 5/40 | 0.001* |
| Status at last following up | |||
| Deceased | 26 | 25 | |
| Live | 6 | 20 | 0.016* |
*
p<0.05