Table 2. Correction between protein expression and clinical characteristics.
| Clinicopathological characteristics | Differentially expressed proteins* | |
|---|---|---|
| up-regulated | down-regulated | |
| Gender (male vs female) | Cdk6, MetAP-2 | Bak, Calretinin, Flk-2 |
| Tumor location (distal vs proximal) | ADAM-10 | Notch4, Caspase-1 |
| Histology grade (poor vs moderate) | ADAM-10, FOXM1 IGF-Irβ, RANKL, Cyclin B1 | DPYD, Maspin |
| Tumor size (≥5cm vs <5cm) | Vimentin, Endoglin, Autotaxin | NOS2 |
| Vascular invasion (present vs absent) | Annexin A1, SK3 | DPYD, p-PKC α/βII |
| Hepatic metastasis (present vs absent) | Bcl-2 | eIF4B, IL-6, Rho A |
*
up-regulated indicates an increased protein expression and down-regulate indicates a decreased protein expression in the former group when compared with the latter group in each category.