Figure 1. Altered expression of PRSS8 in esophageal squamous cell carcinoma (ESCC).
A. PRSS8 expression in normal esophagus, cancer-in-situ, cancer stromal, well-differentiated, moderate-differentiated and poorly-differentiated ESCC. (Blue arrows indicated the positive epithelial staining, red arrows indicated positive stromal staining areas, black arrow indicated no or weak stromal staining area). B. PRSS8 expression levels in ESCC were significantly associated with overall survival time (left panel) and disease free period (right panel) of the patients with ESCC.