Skip to main content
. 2016 Apr 12;7(19):28556–28569. doi: 10.18632/oncotarget.8699

Figure 1. Differential miRNA expression can be detected between benign, premalignant, and malignant pancreatic lesions in EUS-FNAs.

Figure 1

Displayed are the expression levels across tissue-types for (A) miR-21, (B) miR-10b, (C) miR-155, (D) miR-210, (E) miR-135/miR-24 and (F) miR-196a. Total RNA was isolated from EUS-FNAs and quantitative real-time reverse-transcription PCR (qRT-PCR) was used to quantify miRNA expression levels. Small nuclear RNA U6 was used as an endogenous control. Scatterplots are shown for each miRNA and the horizontal lines represent the mean expression level and standard deviation. Four groups of pancreatic lesion had EUS-FNA: benign/inflammatory/pseudocysts (n = 18); mucinous cysts (n = 10); invasive IPMNs (n = 9) and PDAC (n = 18). One-way analysis of variance (ANOVA) was used to compare miRNA levels between tissue-types, followed by Tukey's multiple comparison test (***P < 0.001; **P < 0.01; *P < 0.050). Two-tailed Student's t-test was used to compare benign vs. malignant groups.