Table 1. FGFR2 expression in primary GC tissues correlates with tumorigenicity in nude mice.

In xenograft	FGFR2−/low	FGFR2+/hi	Subtotal	P value
#Tumorigenic (n)	2	14	16	< .01
#Nontumorigenic (n)	68	21	89	< .001
Subtotal	70	35	105	na

Number of tumorigenic and non-tumorigenic patient-derived gastric carcinoma tissue specimens in the nude mouse xenograft assay according to FGFR2 expression patterns.

*FGFR2-/low or FGFR2+/hi, negative/low or postive/high expression in primary GC by in situ immunohistochmistry (IHC); #Tumor mass was formed (tumorgenic) or not formed (nontumorigenic) in tested 3 nude mice for each individual patient's specimen within 16 weeks post subcutaneous injection of approximately 0.2 cm3 GC tissue blocks; n, the number of patient-derived gasric carcinoma speciment belonging to the indicated category.