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(a) The chemical structure of FNA having two dibenzocyclooctyl (DBCO) functionalities for further azide coupling, (b) Conjugation of azide labeled Aβ(14–23) with FNA via metal-free click chemistry, (c) The cartoon showing Aβ(14–23) conjugated FNA tether; the red triangle, black line and blue lines indicate biotin, FNA tether and Aβ(14–23) peptide respectively (d) ESI mass spectra of HPLC pure FNA Aβ(14–23) dimer.
