Firing rates of pyramidal cell subcategories, with and without RAM stimulation. S, Spontaneous firing; G, firing during global stimulation; L, firing rates during local stimulation. The firing rate of superficial cells was insensitive to the presence or absence of stimulation (F = 1.17; df = 2.88; p = 0.32; one-way ANOVA; n = 29). The presence of RAM stimulation did significantly increase the firing rates of intermediate cells (F = 4.19; df = 2.75; p = 0.02; one-way ANOVA; n = 26). Firing frequency during local stimulation was significantly greater than spontaneous, but firing frequency during global stimulation was not. RAM stimulation also significantly increased the firing rates of deep cells (F = 4.42; df = 2.63; p = 0.02; one-way ANOVA; n = 22). Firing frequency during local stimulation was significantly greater than spontaneous, but firing frequency during global stimulation was not. Error bars indicate 1 SEM.