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. Author manuscript; available in PMC: 2016 Oct 6.
Published in final edited form as: J Neurophysiol. 2007 Jul 5;98(3):1526–1537. doi: 10.1152/jn.00564.2007

FIG. 5.

FIG. 5

Carbachol activates muscarinic receptors in vitro. A: carbachol leads to a −4-mV depolarization of the membrane potential from a subthreshold level leading to spiking (spikes truncated at −35 mV). B: atropine eliminates the effects of carbachol, suggesting mAChR activation. C: ISI histogram showing an increase in ISI’s <10 ms after carbachol application. D: significant increase in the burst fraction (fraction of ISIs <10 ms) after carbachol application. E: carbachol also leads to an increased membrane resistance. F: carbachol in the presence of atropine does not increase the membrane resistance.