Table 5.
Final models from mixed model analysis of fractional anisotropy values for group, age, and time of scan for left and right hemisphere pathways
| Within‐subjects effects | Between‐subjects effects | |||||
|---|---|---|---|---|---|---|
| Group × time × age | Time × age | Time × group | Time | Group | Age | |
| Pathway and hemisphere | df (1,30) F (p) | df (1,30) F (p) | df (1,30) F (p) | df (1,30) F (p) | df (1,83) F (p) | df (1,83) F (p) |
| Superior longitudinal | ||||||
| Left | 5.16 (0.030) | 0.05 (0.817) | 5.97 (0.021) | 11.34 (0.002) | 1.72 (0.193) | 9.15 (0.003) |
| Right | 74.11 (<0.0001) | 10.76 (0.002) | 12.19 (0.001) | |||
| Inferior longitudinal | ||||||
| Left | 4.88 (0.035) | 0.20 (0.657) | 5.91 (0.021) | 3.69 (0.064) | 0.20 (0.007) | 3.69 (0.654) |
| Right | 42.61 (<0.0001) | 30.17 (<0.0001) | 9.34 (0.003) | |||
| Inferior frontal occipital | ||||||
| Left | 4.67 (0.039) | 1.49 (0.231) | 5.20 (0.030) | 6.99 (0.013) | 0.28 (0.597) | 6.64 (0.012) |
| Right | 42.6 (<0.0001) | 26.34 (<0.001) | 12.32 (0.001) | |||
| Uncinate | ||||||
| Left | 4.51 (0.042) | 6.32 (0.012) | 4.76 (0.037) | 16.55 (<0.001) | 0.96 (0.331) | 4.75 (0.032) |
| Right | 32.83 (<0.0001) | 23.03 (<0.0001) | 4.62 (0.035) | |||
| Cingulum | ||||||
| Left | 27.37 (<0.0001) | 17.60 (<0.0001) | 6.61 (0.012) | |||
| Right | 45.42 (<0.0001) | 14.95 (0.001) | 10.92 (0.001) | |||
| Cingulum hippocampal | ||||||
| Left | 4.13 (0.051) | 0.14 (0.707) | 4.02 (0.054) | 2.27 (0.143) | 0.060 (0.811) | 8.24 (0.005) |
| Right | 18.02 (0.001) | 16.75 (<0.0001) | 9.57 (0.003) | |||
| Corticospinal | ||||||
| Left | 16.83 (0.001) | 15.44 (0.001) | 6.28 (0.014) | |||
| Right | 31.85 (<0.0001) | 18.14 (<0.0001) | 3.06 (0.084) | |||