Fig. 1. Construction of anti-Leishmania vaccine antigens used for ex vivo stimulation of canine whole blood.
L111f is an 111kD fusion protein produced from a fusion of the L. major homologue of eukaryotic thiolspecific antioxidant (TSA), the L. major stress inducible protein-1 (LmSTI1) and the L. braziliensis elongation and initiation factor (LeIF) genes. NS is a 75kD fusion protein produced from the L. infantum nucleoside hydrolase (NH) and L. infantum sterol 24-c-methyltransferase (SMT) genes.