Table 2. Profiles of 16 dogs with T-zone lymphoma.
| Median | Range | ||
|---|---|---|---|
| Age (years) | 8 | 6–11 | |
| Body weight (kg) | 26.4 | 3.9–39.2 | |
| No of cases | % | ||
| Sex | |||
| Male castrated | 2 | 13 | |
| Female spayed | 4 | 25 | |
| Male intact | 7 | 44 | |
| Female intact | 3 | 19 | |
| Breed | |||
| Golden Retriever | 9 | 56 | |
| Shih Tzu | 3 | 19 | |
| Others | 4 | 25 | |
| Stage | |||
| I | 0 | 0 | |
| II | 1 | 6 | |
| III | 3 | 19 | |
| IV | 2 | 13 | |
| V | 10 | 63 | |
| Substage | |||
| a | 13 | 81 | |
| b | 3 | 19 | |
| Immunological phenotype | |||
| T | 15 | 94 | |
| T, B | 1 | 6 | |
| PARR | |||
| Clonal rearrangement for TCRγ gene | 4 | 25 | |
| Clonal rearrangement for IgH gene | 0 | 0 | |
| Clonal rearrangement for TCRγ & IgH genes | 1 | 6 | |
| Negative | 3 | 19 | |
| Not determined | 8 | 50 | |
| Enlarged lymph node | |||
| Systemic | 16 | 100 | |
| Local | 0 | 0 | |
| Clinical symptom | |||
| Enlargement of spleen or liver | 8 | 50 | |
| Cutaneous lesion | 6 | 38 | |
| Pale mucous membranes | 4 | 25 | |
| Reduction in activity and appetite | 2 | 13 | |
| Respiratory distress | 2 | 13 | |
| Hematological abnormality | |||
| Anemia | 2 | 13 | |
| Leukocytosis | 6 | 38 | |
| Lymphocytosis | 10 | 63 | |
| Thrombocytosis | 4 | 25 | |
| Chemotherapy | |||
| CHOP-based protocola) | 2 | 13 | |
| M-P protocolb) | 6 | 38 | |
| Prednisolone alone | 2 | 13 | |
| No treatment | 6 | 38 | |
a) CHOP-based protocol: cyclophosphamide, doxorubicin, vincristine and prednisolone. b) M-P protocol: melphalan and prednisolone.