Figure 3.

Overall abundance of specified amino acids and distribution around the N-terminus of protein sequences of human and yeast. The abundance of all amino acids was examined on entire protein sequences, as well as on the second, third and fourth positions following the initial Met. A. The abundance in human (H. sapiens) proteins (n=10,790). B. The abundance in yeast (S. cerevisiae) proteins (n=4,819). In both cases Leu was the most abundant amino acid in the overall calculation (although not significantly higher than other amino acids). However, Ala and Ser was the most abundant amino acid on the second position in human (22.9%) and in yeast (23.7%), respectively. In both of human and yeast, no significant deviation was found for either Ala or Ser from the overall abundance of these amino acids in the proteome.