. 2012 Jan 28;9(6):218–228. doi: 10.1016/S1672-0229(11)60025-9

Table 2.

Major trends in synonymous codon usage in L. donovani, L. infantum and L. major as revealed by COA on amino acid usage of encoded proteins on Axis 1 and Axis 2

Organism	Axis 1			Axis 2
Organism	Total variability	Source of variation	Correlation coefficient (r)^a	Total variability	Source of variation	Correlation coefficient (r)^a
L. donovani	32%	CAI	–0.599	20%	Aromaticity	–0.792
		N_C	0.540		Gravy	–0.717
		GT_3S	–0.541
		GC₁₂	0.767
L. infantum	24.2%	CAI	–0.645	14.3%	Aromaticity	0.397
		N_C	0.430		Gravy	0.334
		GC_3S	–0.424
		GC₁₂	0.946
L. major	30%	CAI	0.529	14.3%	Aromaticity	0.669
		GC_3S	0.400		Gravy	0.531
		GC₁₂	–0.862

All correlations are significant at P=0.01. GC₁₂: G/C content at first and second codon sites; CAI, codon adaptation index.