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Effects of ERK1/2 direct inhibitor SCH772984 on HBO induced HSP32 expression. Neurons were pretreated with SCH772984 (10 μM) 30 min before HBO exposure. The phosphorylation of ERK1/2 was detected immediately after HBO exposure (A) and the expression of HSP32 was detected 12 h later (B). Significance compared with Air group, **p<0.01; significance compared with HBO group, ††p<0.01.
