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. 2016 Sep 24;10:108–118. doi: 10.1016/j.redox.2016.09.011

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 6. — Effects of MEK1/2 inhibition on the expression of HSP32 induced by HBO. The phosphorylation of MEK1/2 was detected after HBO exposure (A). Neurons were pretreated with U0126 (10 μM) or trametinib (10 μM) 30 min before HBO exposure, and the phosphorylation of MEK1/2 was detected immediately after HBO exposure (B), the expression of HSP32 was detected 12 h after HBO exposure (C). Significance compared with Air group, **p<0.01; significance compared with HBO group ^††p<0.01. MEK1/2, mitogen-activated and extracellular signal-regulated kinases; Seq, sequence.