Table 2.
Parameter | Model estimates (%RSE) |
---|---|
CL (mL/day) | 208 (3.9) |
Vss (mL) | 5250 (NA) |
ka (day−1) | 0.312 (6.6) |
Lag time (day) | 0.177 (3.4) |
F | 0.761 (4.6) |
%RSE: percentage relative standard error, calculated as (standard error/mean) × 100%; Vss: volume of distribution at steady-state; NA: not applicable; ka: first-order absorption rate constant; F: bioavailability.