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. 2016 Oct 7;6:34832. doi: 10.1038/srep34832

Figure 3. Effects of UREprel, URE and CA on pain behaviours induced by CCI.

Figure 3

(a) Sensitivity to a noxious mechanical stimulus as measured by the Paw-pressure test. (b) Pain threshold to a non-noxious mechanical stimulus as measured by the Von Frey test. (c) Sensitivity to a noxious thermal stimulus as measured by the Plantar test. (d) Pain assessed by hind limb weight bearing alterations using an Incapacitance test. All behavioural tests were performed 7 and 14 days after operation, 24 h after the last treatment. Vegetal extracts and CA were administered p.o. and i.p., respectively; control animals were subjected to sham surgery and treated with vehicle. Treatments were performed daily starting on the day of surgery. Each value represents the mean ± SEM of 10 rats per group, performed in 2 different experimental sets. ^^^P < 0.001 versus sham + vehicle; *P < 0.05, **P < 0.01 and ***P < 0.001 versus CCI + vehicle; §P < 0.05 versus CCI + UREprel.