Figure 6.

Average ω estimates based on the six methods with the consideration of divergence time (t) that varies from 0.1 to 1. We considered the typical values for purifying selection, neutral mutation, and positive selection as ω=0.3 (A, D, G), ω=1 (B, E, H), and ω=3 (C, F, I), respectively. Three different combinations of κ_R and κ_Y were examined: κ_R=1, κ_Y=10 (A, B, C); κ_R=10, κ_Y=1 (D, E, F); κ_R=κ_Y=3.75 (G, H, I). The values of a used for the six methods are listed in Table 2.