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. 2016 Oct 7;6:34719. doi: 10.1038/srep34719

Figure 1. Loss of hepatic JAK2 leads to profound hepatic steatosis.

Figure 1

(a) Body weights of mice at 12 and 40 weeks of age (n ≥ 4/genotype for each time point) (b) Liver weight (LW)/body weight (BW) ratio of mutant and WT mice at indicated time points (n ≥ 4/genotype). (c) Liver damage was quantified by measuring serum levels of the liver enzymes ALT and AST at indicated time points (n ≥ 4/genotype). (d) H&E staining of liver sections at indicated time points. (e) Histopathological analysis assessing medio- and microvesicular steatosis (n ≥ 4/genotype). *p < 0.05, **p < 0.01 and ***p < 0.001.