Table 1.
Representation of amino acid residues in three positions of different TBEV subtypes E protein
| Amino acid residue and its position in the E protein | Number of strains of different TBEV subtypesa | Total | |||||
|---|---|---|---|---|---|---|---|
| 313 | 317 | 331 | E | FE | S | ND | |
| A | T | T | 67 | 19 | 86 | ||
| T | T | T | 1 | 28 | 7 | 36 | |
| T | V | T | 3 | 2 | 5 | ||
| A | I | T | 2 | 2 | 4 | ||
| T | I | T | 2 | 2 | |||
| T | I | A | 54 | 1 | 56b | 111 | |
| T | A | A | 1 | 1 | |||
| T | T | A | 4 | 5c | 9 | ||
| T | A | S | 2 | 6 | 8 | ||
| T | A | T | 55 | 80 | 135 | ||
| Total number of strains | 61 | 58 | 100 | 179 | 397 | ||
a) E is European subtype, FE is Far-Eastern subtype, S is Siberian subtype, ND is “not determined”, e.g. the subtype is not specified in amino acid sequence annotation and in the corresponding article. The most common variants are shown in bold, genotypes are listed according to the sequence authors
b)Strain 886-84, which was annotated as genotype 5 in [25], belongs to this group
c)Strain 178-79, which was annotated as genotype 4 in [25], belongs to this grou