Table 1.
Mechanisms associated with compositional dynamics of eubacterial genomes
| Mechanism | In-Track/Op-Track | GC-content/R-content | Mutation/selection | Selected Ref. |
|---|---|---|---|---|
| Global repair and replicationa | +++/++ | +++/++ | +++/++ | [2], [3], [7], [8] |
| Transcription-coupled DNA repair and transcriptiona | +/++ | ++/+ | ++/+ | [16], [20], [21], [22], [23] |
| Strand-biased nucleotide compositiona | ++/+ | +/++ | ++/+ | [4], [5], [6], [7], [8], [9], [10] |
| Strand-biased gene distributionb | +/++ | +/++ | +/++ | [4], [6], [8] |
| Horizontal gene transfer/transpositionb | +/++ | +/+ | +/++ | [8] |
| Genome size expansionb | +/++ | ++/+ | +/++ | [4], [8] |
| Environmental biotic and abiotic factors | +/+ | +/+ | +/+ | [7] |
Note: Some relevant molecular mechanisms and their impacts on the informational (In-Track) or (/) operational (Op-Track) tracks, GC- or R (purine)-contents, and mutation or selection are scored qualitatively (weakly positive, +; moderately positive, ++; and strongly positive, +++). A limited number of examples are provided as references (parentheses). Mechanisms related to composition alteration and those related to gene alteration are indicated by a and b, respectively.