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. 2015 Aug 26;11(12):2904–2912. doi: 10.1080/21645515.2015.1075680

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Figure 1. — Time course of serum anti-F protein IgG in cotton rats. Cotton rats were intranasally immunized with 3 doses of vaccine (filled arrows) followed by a live viral challenge with RSV A2 (open arrows). Serum anti-F protein IgG end point titers were determined in cotton rats vaccinated with a dose of 3.2 × 10⁵ PFU RSV L19 (6.6 µg F protein) formulated in (A) W₈₀5EC or (B) P188. The results are presented as the geometric mean titer ± 95% confidence interval (CI) (n = 8 cotton rats per group).