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. 2015 Sep 23;67(10):2759–2770. doi: 10.1002/art.39234

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© 2015 The Authors. Arthritis & Rheumatology is published by Wiley Periodicals, Inc. on behalf of the American College of Rheumatology.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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As‐observed and patient‐ and parent‐reported outcomes over time. A and B, Mean Child Health Questionnaire (CHQ) physical summary (PhS) scores (A) and mean CHQ psychosocial summary (PsS) scores (B). On the x‐axis, A, B, and C indicate the 3 study periods. The broken horizontal lines represent a standardized mean score of 50 (and 1 SD below [score of 40]) for the normative population (see ref. 22). C, Parent's global assessment of pain over time. n = the number of patients with available data at each visit day. DB = double‐blind outcomes during the open‐label long‐term extension (LTE) phase. Data were derived from an as‐observed analysis based on all patients who entered the LTE phase.