Fig 4.

A, Two weeks after grafting. There were keratinocytes made of JACE above, and a dermis-like tissue made of artificial dermis below. Keratinocytes were thin and flat. Desmosomes were fewer and narrow (small arrowhead). The density of the dermal layer was low. B, Four weeks after grafting. There were various forms of keratinocytes. Desmosomes became thicker, and the number has increased (right arrows). C, Six weeks after grafting. Both keratinocytes and dermal layer were almost the same as autografts. There were a lot of desmosomes (small arrowheads). The density of the dermal layer was very high.