Table 1.
Relationship between TNF-α expression and clinicopathological features of CC
| Parameters | TNF-α expression
|
||
|---|---|---|---|
| Low, n (%) | High, n (%) | P-value | |
| Age (years) | |||
| <61 | 26 (54.2) | 22 (48.5) | 0.955 |
| ≥61 | 23 (54.8) | 19 (45.2) | |
| Sex | |||
| Male | 30 (48.4) | 32 (51.6) | 0.086 |
| Female | 19 (67.9) | 9 (32.1) | |
| T stage | |||
| T1 + T2 | 8 (53.3) | 7 (46.7) | 0.925 |
| T3 + T4 | 41 (54.7) | 34 (45.3) | |
| Lymph node | |||
| N0–N2 | 35 (56.5) | 27 (43.5) | 0.569 |
| N3–N4 | 14 (50) | 14 (50) | |
| Metastasis | |||
| Negative | 48 (54.5) | 40 (45.5) | 0.898 |
| Positive | 1 (50) | 1 (50) | |
| TNM stage | |||
| I + II | 18 (52.9) | 16 (47.1) | 0.823 |
| III + IV | 31 (55.4) | 25 (44.6) | |
| Pathological grade | |||
| Low and medium | 18 (51.4) | 17 (48.6) | 0.647 |
| High | 31 (56.4) | 24 (43.6) | |
| Pathological type | |||
| Ductal adenocarcinoma | 31 (58.5) | 22 (41.5) | 0.356 |
| Others | 18 (48.6) | 19 (51.4) | |
| Survival status | |||
| Alive | 27 (69.2) | 12 (30.8) | 0.014 |
| Dead | 22 (43.1) | 29 (56.9) | |
Note: Data in bold indicates statistical significance (P<0.05).
Abbreviations: TNF-α, tumor necrosis factor-alpha; CC, colon cancer; TNM, tumor–node–metastasis.