Table 3.
Cellular toxicity of saxitoxin derivatives (fg STX eq. cell−1) from culture experiments conducted with the Northport Bay (NPB8) Alexandrium strain.
| Saxitoxin derivatives fg STX eq cell −1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| C1, C2 | Neo | dcSTX | STX | GTX1, 4 | GTX5 | dcGTX2, 3 | GTX2, 3 | Total | |
| Experiment #2 | |||||||||
| 390μatm | 519 (90) | 165 (136) | n.d. | 112 (25) | 343 (6) | 141 (73) | n.d. | 133 (13) | 1253 (21) |
| 1200μatm | 626 (67) | 286 (101) | n.d. | 161 (83) | 706 (90)* | 197 (29) | n.d. | 165 (34) | 2141 (383)* |
| Experiment #4 | |||||||||
| 390μatm | 188 (47) | 76 (45) | n.d. | 34 (10) | 334 (84) | 45 (11) | 5 (1) | 84 (20) | 765 (213) |
| 1500μatm | 355 (205) | 228 (139) | n.d. | 47 (36) | 750 (252)* | 76 (44) | 8 (6) | 108 (56) | 1383 (395)* |
Values represent the mean (SD) of triplicate or quadruplicate measurements. Asterisks indicate significant differences (p<0.05) between treatments and the control (~390μatm).